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The discovery of the role of the pancreatic circadian clock in insulin and glucose homeostasis

We refer to these multi-omics integrative approaches as physiolomics (e.g., patch-sequencing, spatial RNA-seq following in vivo imaging) or phenotomics (e.g., behavioral profiling, brain activity mapping, and clinical or pathological diagnoses)

Food Function, 7 (7), 33903401

To learn more about how perturbation in LYPLAL1 function contributes to MASLD, we analyzed rare loss-of-function LYPLAL1 mutations using UK BioBank (UKBB) Whole Exome Sequencing (WES) data and knocked out LYPLAL1 in human liver cells to investigate its role in MASLD